Gut microbiome stool test

DNA sequencing of a stool sample that lists your gut microbes — a snapshot, not a cancer screen, an infection test or a treatment guide.

Last updated October 2026 · New Dawn Health editorial team

Sample
Stool, from a kit the clinic provides
Method
DNA sequencing (NGS); 16S or shotgun confirmed when booking
Radiation
None — a lab test on a stool sample
Best use
A snapshot for curiosity; not screening, diagnosis or a treatment guide

What is a gut microbiome test?

Your gut is home to a large community of bacteria and other microbes, called the gut microbiome. A gut microbiome test reads the microbial DNA in a small stool sample. The lab then reports which microbes it found, each as a share of the total.

New Dawn Health offers the FloraUp® Microbiome Gut Health Analysis at iHope Clinic in Taipei. The clinic provides the stool kit and sends the sample to a laboratory for next-generation sequencing (NGS). The package description lists these report sections:

  • Enterotype: the broad community type your sample resembles
  • Beneficial and harmful bacteria: the balance between groups the report labels each way
  • Synthesis capability: for short-chain fatty acids (SCFAs) and for vitamins
  • Intestinal age and a health-risk assessment

16S or shotgun: which kind of sequencing?

Labs sequence stool in one of two ways. An international expert consensus published in 2025 accepts both, with different strengths:

Two accepted ways to sequence a stool sample.
Feature 16S amplicon sequencing Shotgun (whole-genome) sequencing
What is read One bacterial marker gene (16S rRNA) All the DNA in the sample
Naming detail Genus, sometimes species Species, sometimes strain
Microbial genes and functions Not measured Measured
Your own DNA in the data Hardly any Some, which labs filter out
Cost per sample Lower Higher

Which method this test uses is confirmed when you book. It decides how fine-grained the report can be.

What can a stool microbiome test tell you today?

It can describe which microbes were in one sample. Turning that description into health advice is where the evidence runs out.

The 2025 consensus was written by 69 experts from 18 countries and published in The Lancet Gastroenterology & Hepatology. It found no direct evidence that microbiome tests improve how patients are managed.

What each part of the report can mean

The report's sections and what the evidence supports.
Report section What the evidence says
Microbe list and diversity The consensus treats these as the core of any test. How diversity should guide care is not yet clear.
Enterotype Proposed in 2011 as three distinct community types. A 2014 reanalysis found the types blend into each other and can shift within one person.
Beneficial and harmful bacteria The consensus calls the evidence for a causal link between specific microbes and human disease limited.
SCFA and vitamin capability The consensus discourages estimating "metabolic potential" from which bacteria are present. Ask how these scores are made.
Intestinal age and health-risk scores These are the company's own models. The consensus found too little evidence for any overall gut-imbalance (dysbiosis) score.

Would another lab read the same sample the same way?

Not reliably. In a 2026 study led by the US National Institute of Standards and Technology (NIST), seven consumer testing services each received three kits of the same well-mixed stool. What came back:

  • Differences between services were as large as differences between different people.
  • Depending on the service, the same material was reported to hold from 20 to 1,701 species.
  • One service called the same material healthy twice and unhealthy once.

Is there a "normal" gut microbiome?

Not one that science can define today. The Human Microbiome Project found that the main gut microbes vary widely in kind and amount, even among healthy people.

What those microbes can do varied much less: different mixes of species carried similar sets of metabolic pathways. Expert reviews since then agree:

  • No agreed healthy composition: a 2024 review in Science found no consensus on what a healthy microbiome looks like, in any population.
  • No strict reference ranges: the 2025 consensus says there is not enough information to set healthy ranges for each species.
  • No agreed definition of imbalance: "dysbiosis", the term for an unbalanced microbiome, has no common definition.

Is it a test for colorectal cancer or infection?

No. A general microbiome profile does not screen for cancer, and it does not diagnose infection. Each of those questions has its own test.

What a microbiome profile can show
  • Which microbes were in one sample, as shares of the total
  • Diversity: how many kinds there were, and how evenly they were spread
  • Known disease-causing microbes, if the lab reports them
  • A baseline to compare with a later sample from the same lab
What it cannot do
  • Screen for colorectal cancer. A FIT stool test, on the urine and stool tests page, or a colonoscopy does that.
  • Find the infection behind diarrhea. A stool culture or PCR panel, ordered by a doctor, does that.
  • Test for H. pylori. The H. pylori stool test, on the urine and stool tests page, does that.
  • Choose a probiotic or treatment. No test does that yet; see the section on acting on a result below.

How is the colon screened instead?

Colorectal cancer screening in the US and in Taiwan.
US (USPSTF, 2021) Taiwan (HPA, from 2025)
Who Adults 45 to 75; selectively 76 to 85 Ages 45 to 74; 40 to 44 if a parent, child or sibling had colorectal cancer
Tests Stool tests (FIT, guaiac or stool DNA-FIT), or colonoscopy, CT colonography or sigmoidoscopy A free FIT stool test every two years; colonoscopy if it is abnormal
Microbiome profile Not one of the listed tests Not part of the program

Taiwan's free FIT is for people with National Health Insurance, who collect the tube at a contracted clinic. The gastrointestinal health page covers colon and stomach screening in more detail.

Research is testing purpose-built panels of stool bacteria for colorectal cancer. An Asia-Pacific guideline (APAGE–APSDE, 2023) says panels including Fusobacterium nucleatum have potential to screen for advanced colon growths. If the FloraUp® risk assessment mentions colorectal cancer, ask which validated panel it uses.

Infections need their own tests

Infections that cause diarrhea are found with targeted tests that a doctor orders. A stool culture, for example, looks for germs behind severe bloody diarrhea with fever, or diarrhea that will not go away. The consensus calls culture and PCR panels the tools for finding specific germs, distinct from microbiome profiling.

Who might consider it, and who should start elsewhere?

The package description suggests the test for people with irregular eating, digestive discomfort, long-term medicines, or curiosity about their health. The consensus is narrower: it suggests that a doctor or another licensed professional, such as a dietitian, requests the test.

A better first step, by situation.
Your situation A better first step
Curious, with no symptoms The test can satisfy curiosity. Read it as a snapshot, not a health verdict.
Bloating, pain or bowel changes that keep coming back A doctor's assessment first. The report is not a diagnosis.
Any of the warning signs above, such as blood in the stool See a doctor promptly. A colonoscopy or a stool culture may be needed.
Due for colorectal screening A FIT stool test or a colonoscopy, the established screens.
Irritable bowel syndrome (IBS), Crohn's disease or ulcerative colitis Your specialist. AGA guidance limits probiotics for these conditions to clinical trials.

How do I prepare and collect the sample?

  1. 1
    When you book
    Tell your coordinator about any antibiotics in the past three months, and every probiotic, prebiotic and supplement you take. Expert consensus asks testing providers to record these.
  2. 2
    In the days before
    Keep your usual diet and medicines. Expert consensus advises against stopping a therapy or changing your diet unless your doctor says so, because it gives a false picture.
  3. 3
    Collecting the sample
    Follow the kit instructions so the sample is not contaminated. Note the time you collected it and how it was stored.
  4. 4
    Returning the kit
    Return it within the time the kit allows. Your coordinator confirms where and when to hand it in.

Antibiotics and probiotics

Antibiotics reshape the gut microbiome for weeks. In a 2018 study, 12 healthy men took a 4-day course of three last-resort antibiotics. Researchers then followed their gut microbes for six months:

  • Bifidobacterium species and butyrate-producing bacteria were depleted at first.
  • The community returned close to its starting mix within about 1.5 months.
  • Nine common species were still undetectable in most of the men after six months.

So a sample taken soon after antibiotics shows a recovering microbiome, not your usual one. Ask the clinic whether to wait, and never cut a prescribed course short for the test. Probiotics and supplements are recorded rather than stopped, unless your doctor advises otherwise.

At home or at the clinic?

Expert consensus expects stool to be collected at home, into a tube with a DNA preservative. Stool without a preservative has to be shipped within 24 hours on ice or dry ice, and is more prone to error.

The package lists a duration of 30 minutes. For a visitor to Taipei, three details are confirmed when you book:

  • Whether you collect the sample at the clinic, or later at your hotel with the kit
  • How many hours you have to return it, and whether it must stay cool
  • Whether a kit can travel home with you and be sent back

What can a result sensibly change, and what should it not drive?

Diet can change the gut microbiome's makeup, the consensus notes. In a 2014 study in Nature, a short switch to an all-plant or all-animal diet changed which gut bacteria thrived.

The effects are not always the expected ones. In a 17-week randomized study, a high-fermented-food diet raised microbiome diversity, while a high-fiber diet left it unchanged.

Which steps a microbiome report can reasonably feed into.
Possible step Reasonable? Why
Eat more fiber-rich plant foods Yes, for most adults MedlinePlus advises 21 to 38 grams of fiber a day, added over a few weeks. This holds with or without a test.
Repeat the test after a diet change Possibly The consensus says repeat samples may help in some situations. Compare results from the same lab only.
Buy probiotics or supplements the report suggests No The consensus discourages treatment advice from testing companies. AGA recommends probiotics for IBS, Crohn's disease and ulcerative colitis only in clinical trials.
Take antibiotics to clear “harmful” bacteria No Treatment changes based on a test should come only from your own doctor.
Have a fecal microbiota transplant (FMT) No AGA suggests against FMT for IBS or inflammatory bowel disease outside clinical trials.
Stop or change a prescribed medicine No Expert consensus says stopping a drug before testing could be clinically contraindicated.
Skip colorectal screening No A microbiome result does not replace a FIT stool test or a colonoscopy.

What are the risks?

Collecting a stool sample carries no physical risk. The risks come from what a report leads people to do:

  • Wrong conclusions: self-misdiagnosis, and delay in seeking medical care, as a 2024 review in Science describes.
  • Swapped treatment: taking supplements in place of prescription medicines, from the same review.
  • Upselling: about 45% of the 31 consumer testing companies that review identified sell supplements they recommend from results.
  • Privacy: shotgun data can include some of your own DNA. The consensus says providers should explain whether data may be sold, mined for research or used to train AI.

How much does it cost, and is it covered?

The live price further down this page is the booking price at New Dawn Health for the FloraUp® analysis at iHope Clinic. Any consultation beyond it is confirmed when you book.

  • Tests in Taiwan are self-funded for visitors. Short-term visitors are not covered by Taiwan's National Health Insurance, so this test is self-funded.
  • Reimbursement at home is a question for your insurer. A plan may treat a self-requested microbiome test differently from one a doctor orders. Ask them before you book.

When do results come, and what happens next?

  1. 1
    The report
    Turnaround, report language and who explains the results are confirmed when you book. Ask for a copy you can keep, and for the raw sequence data, which the consensus says can be shared on request.
  2. 2
    In Taiwan
    If the clinic offers a results consultation, ask which findings, if any, need medical follow-up.
  3. 3
    If a disease-causing microbe is listed
    Show the report to a doctor rather than treating yourself. The doctor decides whether a targeted test is needed.
  4. 4
    Back home
    Take the report to your own doctor. Most doctors are not trained to read microbiome reports, the consensus notes, so ask what a result would change before acting on it.
  5. 5
    New or worsening symptoms
    See a doctor, whatever the report says.

What should I ask iHope Clinic before booking?

Ask your coordinator to confirm these before you book:

  • Is the sequencing 16S or shotgun, and how deep is it?
  • Which laboratory runs the test, and which accreditation does it hold?
  • Do I collect the sample at the clinic or at my hotel, and how fast must it be returned?
  • How long after antibiotics should I wait?
  • How are the enterotype, intestinal age, SCFA, vitamin and risk scores calculated, and what study validated them?
  • Which comparison group defines “normal” in the report?
  • Does the report recommend products, and does the testing company sell them?
  • When is the report ready, in what language, and who explains it?
  • Can I have the raw sequence data, is human DNA removed, and can my data be sold or used for research?

Sources & further reading

  1. [1] International consensus statement on microbiome testing in clinical practice (Porcari 2025) — 69 experts, 18 countries; insufficient evidence for routine use; no strict healthy reference ranges; no dysbiosis index; home collection with DNA preservative; no stopping therapy or changing diet before testing — The Lancet Gastroenterology & Hepatology
  2. [2] Evaluating the analytical performance of direct-to-consumer gut microbiome testing services (Servetas 2026) — 7 services, 3 kits each of one fecal standard; 20 to 1,701 species reported — Communications Biology (NIST) / PubMed Central
  3. [3] The DTC microbiome testing industry needs more regulation (Hoffmann 2024) — 31 companies, about 45% sell supplements; no consensus on a healthy microbiome — Science / PubMed Central
  4. [4] Structure, function and diversity of the healthy human microbiome (Human Microbiome Project 2012) — Nature / PubMed
  5. [5] Enterotypes of the human gut microbiome (Arumugam 2011) — three clusters proposed — Nature / PubMed
  6. [6] Rethinking "enterotypes" (Knights 2014) — continuous, and can vary within an individual — Cell Host & Microbe / PubMed
  7. [7] Recovery of gut microbiota of healthy adults following antibiotic exposure (Palleja 2018) — 12 men, 4-day course; near baseline in 1.5 months; 9 species missing at 180 days — Nature Microbiology / PubMed
  8. [8] Diet rapidly and reproducibly alters the human gut microbiome (David 2014) — Nature / PubMed
  9. [9] Gut-microbiota-targeted diets modulate human immune status (Wastyk 2021) — 17-week randomized study; fermented foods raised diversity, fiber did not — Cell / PubMed
  10. [10] Fiber — 21 to 38 grams a day; add gradually over a few weeks — MedlinePlus (NIH)
  11. [11] Clinical practice guidelines on the role of probiotics in the management of gastrointestinal disorders (2020) — IBS, Crohn's disease, ulcerative colitis: only in clinical trials — American Gastroenterological Association
  12. [12] Clinical practice guideline on fecal microbiota-based therapies (Peery 2024) — against FMT for IBD or IBS outside trials — American Gastroenterological Association / Gastroenterology — PubMed
  13. [13] Colorectal Cancer: Screening — recommendation (2021, ages 45–75) — U.S. Preventive Services Task Force
  14. [14] Expanding colorectal cancer screening — free FIT every two years at 45–74, and 40–44 with a family history (2025) — Health Promotion Administration, Ministry of Health and Welfare (Taiwan)
  15. [15] APAGE–APSDE clinical practice guidelines on non-invasive biomarkers for colorectal neoplasia (Chan 2023) — stool microbial marker panels — Gut / PubMed Central
  16. [16] Colon Cancer Treatment (PDQ) — signs: blood in the stool, a change in bowel habits — National Cancer Institute
  17. [17] Stool culture — for severe bloody diarrhea with fever, or diarrhea that does not go away — MedlinePlus (NIH)

Gut microbiome stool test — Frequently Asked Questions

Can a gut microbiome test find colon cancer?

No. Colorectal cancer is screened with a FIT stool test or colonoscopy, under both US (USPSTF) and Taiwan (HPA) programs. Researchers are testing specific bacterial marker panels, but a general microbiome profile is not a cancer screen. Blood in the stool or a lasting change in bowel habits needs a doctor.

Should I stop probiotics, or wait after antibiotics, before the test?

Do not stop probiotics or medicines unless your doctor advises it; expert consensus says that gives a false picture. Tell the team about any antibiotics in the past three months. Antibiotics can shift the microbiome for weeks, so ask the clinic whether to wait.

Is there a "normal" gut microbiome?

Not one science can define yet. Healthy people carry very different mixes of microbes, and the 2025 consensus found too little information to set strict healthy ranges. A report's "normal" means normal against the comparison group that lab chose.

Can the report tell me which probiotic to take?

Not reliably. The international consensus discourages testing companies from giving treatment advice. The AGA recommends probiotics for irritable bowel syndrome, Crohn's disease and ulcerative colitis only within clinical trials. Discuss any change with your own doctor.

Would a different lab give me the same result?

Not necessarily. In a 2026 NIST study, seven consumer services tested the same well-mixed stool. Differences between services were as large as differences between people, and one service called the same material healthy twice and unhealthy once.

Can I collect the sample at my hotel?

Possibly. Expert consensus expects stool to be collected at home in a tube with a DNA preservative. Whether the FloraUp® kit can be collected at a hotel, and how fast it must reach iHope Clinic, is confirmed when you book.

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